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1.Optical Microscopy, Particle size in the range of 0.2 - 100 µm can be, measured. Procedure:, 1. Eye piece of the microscope is fitted with a, micrometer., 2. This eye-piece micrometer is calibrated using a, standard stage micrometer., 3. The powder sample is dispersed in a suitable, vehicle in which it does not dissolve and its, properties.
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Nitrogen gas is commonly employed and the apparatus is quantasorb. A plot of p/V (p-p0) against p/p0 is a straight line with a slope and intercepts b and Vm. Air permeability method. The rate of penetration of a gas or liquid on to the powder is related to resistance to the flow of a liquid through a compact of powder.
Micromeritics
Physical Pharmacy. Chapter # 03. Physico-Chemical Principles. F. Micromeritics. Department of Pharmacy The Islamia University of Bahawalpur. Page | 1 Micromeritics TABLE OF CONTENTS 1. INTRODUCTION 2. PARTICLE SIZE AND SIZE DISTRIBUTION 3. RANGE OF PARTICLE SIZES 4. METHODS FOR DETERMINING PARTICLE SIZE 5. MICROMERITICS APPLICATIONS 6. . IMPORTANCE OF MICROMERETICS IN PHA
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Granular pharmaceutical solids, prepared by 5 different granulation methods, were evaluated on the basis of repose angle, hardness, density, number of particles per gram, bulk density, shape volume factor, bulk volume, and geometrical form. Particular attention was given to the development of an accurate technique for evaluating shape volume factor as a means of characterizing the over-all.
MICROMERITICS & ITS APPLICATION IN PHARMACY
Martin's physical pharmacy and pharmaceutical sciences : physical chemical and biopharmaceutical principles in the pharmaceutical sciences. Colloids -- Coarse dispersions -- Drug delivery -- Micromeritics -- Rheology -- Biomaterials -- Drug delivery systems. Pdf_module_version 0.0.19 Ppi 300 Rcs_key 24143 Republisher_date 20200804020840.
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Definition: It is the science and technology of small particles deals with fundamental and derived properties of individual and collection of particles In the field of pharmacy, micromertics has become an important area of study because it influences a large number of parameters Research and development manufacturing of dosage forms such as
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Flame extension, including flashback B. Physicochemical characteristics 1. vapor pressure: pressure gauge, water bath, pressure variation from container to container; . density: hydrometer 2 3. moisture content: Karl Fisher method, GC identification of propellants: GC, IR 4. concentrate-propellant ratio: GC 5.
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The word Micromeritics refers to a discipline of science and technology that deals with studies related to the fundamental as well derived properties of particles. A precise knowledge of the particles size is of supreme importance in the pharmaceutical and materials science.
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It is the responsibility of the health care providers to ascertain the FDA status of each drug or device planned for use in their clinical practice. To purchase additional copies of this book, call our customer service department at (800) 638-3030 or fax orders to (301) 223-2320.
Physical Pharmacy Notes Micromeritics PHYSICAL PHARMACY
INTRODUCTION • Micromeritics is the study of fundamental and derived properties of individual as well as a collection of particles and thus can be called the science and technology of small particles. • The particle size of a drug can affect its release from dosage forms that are administered orally, parenterally, rectally and topically.
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Research Article Micromeritics of Granular Pharmaceutical Solids I Physical Properties of Particles Prepared by Five Different granulation Methods Dale E. Fonner, Jr. Gilbert S. Banker, James Swarbrick, School of Pharmacy and Pharmacal Sciences, Purdue University, Lafayette, Ind. School of Pharmacy and Pharmacal Sciences, Purdue University Lafayette Ind Granular pharmaceutical solids, prepared.
Micromeritics
Micromeritics •Micromeritics is the science and technology of small particles. Knowledge and control of the size and the size range of particles are of significant importance in pharmacy because the size and surface area of a particle related to the physical, chemical and pharmacologic properties of a drug.
MICROMERITICS & ITS APPLICATION IN PHARMACY
20 20 More from AdarshPatel73 () Micromeritics 1 - Physical Pharmacy Micromeritics • Micromeritics involve Applications • Release and • Physical stability: Particle 5. Particles - Characteristics • Particles characteristics influence the dissolution rate, absorption rate, content uniformity, taste, texture, color & stability.
Micromeritics and Powder Rheology by Abhijit Debnath Issuu
PHYSICAL PHARMACY MICROMERITICS-- the science and technology of small particles. Methods of Determining Particle Size 1.Optical Microscopy or Microscopic Method - most accurate -- microscope eyepiece fitted with micrometer by which the size of particles may be estimated -- Unit of particle size - micrometer or micron (μm or μ) -- 1 μm or μ = 10 --6 m, 10--4 cm, 10--3 mm
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importance in pharmacy. thus, size, and hence surface area, of a particle can be related in a significant way to the physical, chemical, and pharmacologic properties of a drug. IMPORTANCE OF THE MICROMERITICS: 2
Important MCQs of Micromeritics Unit4 Physical PharmaceuticsII
The word Micromeritics refers to a discipline of science and technology that deals with studies related to the fundamental as well derived properties of particles. A precise knowledge of the particles size is of supreme importance in the pharmaceutical and materials science.